首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡(jiǎn)稱創(chuàng)新中心）是北京市新成立的具有獨(dú)立法人資格的新型研發(fā)機(jī)構(gòu)。創(chuàng)新中心以推動(dòng)醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家及其科研團(tuán)隊(duì)，與首都醫(yī)學(xué)教育和科學(xué)研究?jī)?yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺(tái)，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實(shí)踐新型科研模式和體制機(jī)制，逐步推進(jìn)醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。

一、實(shí)驗(yàn)室介紹

王立銘，首都醫(yī)科大學(xué)公共衛(wèi)生學(xué)院院長(zhǎng)、博士生導(dǎo)師，首都醫(yī)學(xué)科學(xué)創(chuàng)新中心資深研究員、人類遺傳與分子醫(yī)學(xué)研究所所長(zhǎng)。實(shí)驗(yàn)室長(zhǎng)期關(guān)注機(jī)體代謝的神經(jīng)生物學(xué)調(diào)控機(jī)理研究。在Nature、Nature Neuro science、PNAS、eLife、Cell Research等知名期刊發(fā)表多篇研究論文。同時(shí)致力于大眾科學(xué)傳播和教育，出版專著《吃貨的生物學(xué)修養(yǎng)》、《上帝的手術(shù)刀》、《生命是什么》、《笑到最后》、《給忙碌者的病毒科學(xué)》等科普書籍，發(fā)行量超30萬(wàn)冊(cè)，先后獲得國(guó)家圖書館“文津圖書獎(jiǎng)”，科技部全國(guó)優(yōu)秀科普作品，“吳大猷科普著作獎(jiǎng)”等獎(jiǎng)勵(lì)。

二、實(shí)驗(yàn)室研究方向

包括人類在內(nèi)，動(dòng)物的生存和健康很大程度上依賴于對(duì)機(jī)體能量和必須營(yíng)養(yǎng)物質(zhì)水平的精確調(diào)節(jié)和維持，而中樞神經(jīng)系統(tǒng)在這方面發(fā)揮了不可或缺的重要功能。通過(guò)實(shí)時(shí)的感知機(jī)體內(nèi)部的能量和營(yíng)養(yǎng)物質(zhì)儲(chǔ)備，以及環(huán)境中食物的分布，中樞神經(jīng)系統(tǒng)可以通過(guò)精密的行為調(diào)節(jié)，保證動(dòng)物機(jī)體的代謝平衡。而一旦這一調(diào)控機(jī)制被破壞，將可能引發(fā)包括進(jìn)食障礙、肥胖癥在內(nèi)的一系列神經(jīng)和代謝系統(tǒng)疾病。

實(shí)驗(yàn)室對(duì)神經(jīng)系統(tǒng)與代謝系統(tǒng)相關(guān)聯(lián)的生物學(xué)問(wèn)題有廣泛的興趣。近期的研究工作將主要利用定量行為分析、活體鈣成像、遺傳篩選和分析、單細(xì)胞轉(zhuǎn)錄組和環(huán)路追蹤等技術(shù)，在果蠅和小鼠模型中研究如下兩個(gè)相互獨(dú)立但互相關(guān)聯(lián)的生物學(xué)問(wèn)題：

l 神經(jīng)系統(tǒng)如何參與機(jī)體能量和重要營(yíng)養(yǎng)物質(zhì)代謝的調(diào)控

l 動(dòng)物各器官如何協(xié)同參與機(jī)體代謝的調(diào)控和代謝病的發(fā)生

三、代表性文章

Elife. 2023 Sep 12;12:e85365. PMID: 37698486

Cell Res. 2023 Jun;33(6):434-447. PMID: 37055592

Cell Res. 2021 May;31(5):580-588. PMID: 33273704

Elife. 2020 Apr 23;9:e53103. PMID: 32324135

Cell Res. 2018 Oct;28(10):1013-1025. PMID: 30209352

Cell Discov. 2018 Dec 4;4:66. PMID: 30534416

四、崗位信息

01、科研助理

1）主要職責(zé)

1.在導(dǎo)師及合作導(dǎo)師共同指導(dǎo)下參與實(shí)驗(yàn)室的課題研究；

2.協(xié)助處理實(shí)驗(yàn)室公共事務(wù)。

2）任職要求

1.獲得生物學(xué)/基礎(chǔ)醫(yī)學(xué)相關(guān)領(lǐng)域本科或碩士學(xué)位，畢業(yè)時(shí)間一般不超過(guò)三年；

2.有實(shí)驗(yàn)室學(xué)習(xí)經(jīng)歷者優(yōu)先；

3.對(duì)科研工作充滿熱情和自我驅(qū)動(dòng)力、對(duì)代謝和代謝相關(guān)疾病有強(qiáng)烈興趣、有團(tuán)隊(duì)合作精神。

02、博士后

1）主要職責(zé)

1.在導(dǎo)師及合作導(dǎo)師共同指導(dǎo)下參與實(shí)驗(yàn)室的課題研究；

2.協(xié)助處理實(shí)驗(yàn)室公共事務(wù)。

2）任職要求

1.獲得生物學(xué)/基礎(chǔ)醫(yī)學(xué)相關(guān)領(lǐng)域博士學(xué)位，畢業(yè)時(shí)間一般不超過(guò)三年；

2.在生物學(xué)/基礎(chǔ)醫(yī)學(xué)相關(guān)領(lǐng)域有第一作者論文發(fā)表；

3.對(duì)科研工作充滿熱情和自我驅(qū)動(dòng)力、對(duì)代謝和代謝相關(guān)疾病有強(qiáng)烈興趣、有團(tuán)隊(duì)合作精神。

五、福利待遇

1.根據(jù)應(yīng)聘者的工作經(jīng)驗(yàn)和能力，提供具有市場(chǎng)競(jìng)爭(zhēng)力的薪酬（詳情面談）；

2.享受五險(xiǎn)一金、帶薪年假、體檢和補(bǔ)充醫(yī)療保險(xiǎn)等；

3.支持個(gè)人職業(yè)發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)。

六、申請(qǐng)方法

凡符合招聘崗位要求且有意向者，請(qǐng)準(zhǔn)備申請(qǐng)材料：

1.個(gè)人簡(jiǎn)歷

2.學(xué)術(shù)成果及獎(jiǎng)勵(lì)清單

發(fā)郵件至songtingting_ext@cimrbj.ac.cn，請(qǐng)【點(diǎn)擊下方“立即投遞/投遞簡(jiǎn)歷”，即刻進(jìn)行職位報(bào)名】

郵件主題按照“姓名+博士后應(yīng)聘”或者“姓名+研究助理應(yīng)聘”的格式標(biāo)注，初審合格后會(huì)發(fā)出面試通知。

聯(lián)系人：宋老師

聯(lián)系地址：北京市豐臺(tái)區(qū)右安門外西頭條10號(hào)-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心

本招聘長(zhǎng)期有效，至招聘到合適人選為止。

ABOUT CIMR

The Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the Capital Medical University, Beijing, China and committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment. For more information, please visit our website: www.cimrbj.ac.cn

Laboratory Introduction

Liming Wang is the Dean of the School of Public Health at Capital Medical University, a doctoral supervisor, a senior researcher at the Chinese Institutes for Medical Research in Beijing, and the director of the Institute of Human Genetics and Molecular Medicine. His laboratory has long focused on studying the neural and biological regulatory mechanisms of metabolism in the body. He has published numerous research papers in prestigious journals, including Nature, Nature Neuroscience, PNAS, eLife, and Cell Research. Additionally, he is dedicated to science communication and education, having authored popular science books such as Biological Cultivation of Foodies, God's Scalpel, What Is Life, Laughing Until the End, and Virus Science for Busy People, which have collectively sold over 300,000 copies. He has received several prestigious awards, including the Wenjin Book Award from the National Library, the National Excellent Science and Technology Popularization Works Award, and the Wu Daohu Science Popularization Book Award.

Major Research Projects

The survival and health of animals, including humans, largely depend on the precise regulation and maintenance of energy and essential nutrient levels in the body. The central nervous system plays an indispensable role in this process. By continuously monitoring the internal energy and nutrient reserves of the body, as well as the availability of food in the environment, the central nervous system can maintain metabolic balance through precise behavioral regulation. However, when this regulatory mechanism is disrupted, it can result in a range of neurological and metabolic disorders, including eating disorders and obesity.

Our laboratory has a diverse array of interests concerning the biological issues related to the nervous and metabolic systems. Our recent research will concentrate on employing quantitative behavioral analysis, in vivo calcium imaging, genetic screening and analysis, single-cell transcriptomics, and circuit tracking to explore two distinct yet interconnected biological questions in Drosophila and mouse models:

    How does the nervous system regulate energy metabolism and the utilization of essential nutrients?

    How do animal organs synergistically participate in the regulation of metabolism and the development of metabolic diseases?

Representative Publications

Elife. 2023 Sep 12;12:e85365. PMID: 37698486

Cell Res. 2023 Jun;33(6):434-447. PMID: 37055592

Cell Res. 2021 May;31(5):580-588. PMID: 33273704

Elife. 2020 Apr 23;9:e53103. PMID: 32324135

Cell Res. 2018 Oct;28(10):1013-1025. PMID: 30209352

Cell Discov. 2018 Dec 4;4:66. PMID: 30534416

Open Positions

Research Assistant

Main Responsibilities

a. Counducting research project under the guidance of the supervisor and the co-supervisor.

b. Getting involved in laboratory public affairs.

Qualifications

a. A bachelor's degree or a master's degree in biology or a related field of basic medicine, typically completed within three years after graduation.

b. A laboratory learning experience is preferred.

c. Be passionate and self-motivated in scientific research, possess a strong interest in metabolism and metabolic-related diseases, and demonstrate the ability to work collaboratively as a team player.

Postdoctoral Researcher

Main Responsibilities

a. Counducting research project under the guidance of the supervisor and the co-supervisor.

b. Getting involved in laboratory public affairs.

Qualifications

a. A doctoral degree in a related field of biology or basic medicine, typically completed within three years of graduation.

b. First-author papers published in the fields of biology and basic medicine.

c. Be passionate and self-driven in scientific research, possess a strong interest in metabolism and metabolic-related diseases, and demonstrate the ability to work effectively as a team player.

Welfare Treatment

a.Offering a competitive salary that is commensurate with the candidate's work experience and skills, as assessed during a comprehensive interview.

b. Enjoying five types of insurance, a single fund, paid annual leave, a physical examination, and supplementary medical insurance, among other benefits.

c.Supporting personal career development and providing necessary job related professional training.

How to apply

For individuals who meet the qualifications for the recruitment position and are interested, please prepare the necessary application materials:

a. Personal resume

b. List of Academic Achievements and Awards

Please send an email to

songtingting_ext@cimrbj.ac.cn

The subject line of the email should follow the format "Name + postdoc application or Name + research assistant", and an interview notice will be issued following the preliminary examination.

Contact person: Tingting Song

This recruitment is valid for the long term until a suitable candidate is recruited.

信息來(lái)源于網(wǎng)絡(luò)，如有變更請(qǐng)以原發(fā)布者為準(zhǔn)。

來(lái)源鏈接：

https://mp.weixin.qq.com/s/ilVCvJ0jI7DGg9iX5AtBgA

為防止簡(jiǎn)歷投遞丟失請(qǐng)抄送一份至：boshijob@126.com（郵件標(biāo)題格式：應(yīng)聘職位名稱+姓名+學(xué)歷+專業(yè)+中國(guó)博士人才網(wǎng)）