招聘簡介：

　　VIB是比利時法蘭德斯的一家富有創業精神且充滿活力的非營利性研究機構，專注于生命科學領域的突破性研究。 VIB-KULeuven癌癥生物學中心（CCB）是位于比利時魯汶大學醫院校區的VIB研究部門之一。建行擁有11個研究小組，代表約200名國際研究人員，行政和技術合作者。 CCB的重點是揭示癌癥的分子基礎，并在適當的時候利用這些見解來開發新的治療或診斷策略。

　　關于實驗室

　　由Patrizia Agostinis領導的細胞死亡研究和治療實驗室尋求一位積極性高，技術精湛的博士后研究員加入該團隊。我們的團隊正在研究癌癥和基質細胞中的自噬作為腫瘤微環境和抗腫瘤免疫的主要修飾因子。我們最近確定了腫瘤血管相關自噬在癌癥傳播和生長中的關鍵作用。我們現在有興趣揭示自噬如何影響腫瘤 - 基質對話，特別關注腫瘤免疫監測和免疫治療反應。我們的目標是追求創新和跨學科的研究主題，涵蓋從綜合組學到轉化癌癥免疫療法的研究，以利用自噬調節機制獲得治療益處和改進免疫療法。

　　職位描述

　　作為博士后，您將進行基礎和臨床前研究，重點關注基質細胞相關自噬在免疫監視和使用轉基因小鼠模型的抗腫瘤免疫中的作用。您將為博士生提供超級支持和支持，為實驗室的多個研究項目做出貢獻，具有協作精神，并與合作者，臨床醫生，計算生物學家以及技術轉讓專家和行業合作者保持聯系。您需要能夠獨立地組織和排除您的工作，對其進行全面記錄，并以透明和專業的方式與團隊溝通結果和經驗。

　　英文原文：

　　VIB is an entrepreneurial and vibrant non-profit research institute in Flanders-Belgium with a clear focus on ground breaking research in life sciences. The VIB-KULeuven Center for Cancer Biology (CCB), is one of the research departments of VIB located at the University Hospital Campus in Leuven, Belgium. CCB hosts 11 research groups and represents about 200 international research-ers, administrative and technical collaborators. The focus of the CCB is to unravel the molecular basis of can-cer, and whenever suitable, exploit these insights to develop novel therapeutic or diagnostic strategies.

　　About the Lab

　　The Laboratory for Cell Death Research & Therapy, headed by Patrizia Agostinis, seeks a highly motivated and skilled Postdoctoral Researcher to join the team. Our team is studying autophagy in cancer and stromal cells as a main modifier of the tumor microenvironment and anti-tumor immunity. We recently defined a critical role for tumor vasculature-associated autophagy in cancer dissemination and growth. We are now interested in unravelling how autophagy impacts the tumor-stroma dialogue with particular focus on tumor immunosurvelliance and immunotherapy responses. Our goal is to pursue an innovative and interdisciplinary research theme, covering research from integrated omics to translational cancer immunotherapy, in order to harness autophagy regulated mechanisms for therapeutic benefits and for the improvement of immuno-therapy.

　　Job description

　　As a postdoc you will perform basic & preclinical research focused on the role of stromal cell-associated autophagy in immunosurveillance and anti-tumor immunity using transgenic mouse models. You will super-vise and support PhD students and contribute to several research projects of the lab, have a collaborative spirit and liaise with collaborators, clinicians, computational biologists, but also technology transfer experts and industrial collaborators. You need to be able to organise and troubleshoot your work independently, document it thoroughly and communicate results and experiences with the team in a transparent and pro-fessional manner.

　　Profile and skills

　　We are looking for a highly motivated, well organized and dynamic candidate with a high level of independ-ence and creative thinking.

　　You hold a PhD in cancer immunology or related fields

　　You have a publication track record in these fields with at least one first author publication

　　You are eager to learn new techniques and you show a keen interest and curiosity driven approach to

　　scientific questions

　　You have demonstrable practical skills in molecular/cellular biology, isolation and phenotyping on

　　immune cells, T cells analysis in vivo/ex vivo, high-end imaging, analysis of tumor

　　microenvironment. Knowledge and skills related to autophagy pathways is a plus

　　VIB Center for Cancer Biology

　　You have experience in working with deadlines and being involved simultaneously in multiple

　　projects

　　You are a team player with excellent oral and written English communication skills

　　You are able to guide PhD students and coordinate the projects between our teams

　　We offer

　　A 3 to 4 years position based on an annual contract with the possibility of renewal, and depending on a positive evaluation; the candidate will be expected to apply for personal postdoctoral fellowships

　　The job is available immediately, but the starting date is negotiable

　　Access to state-of-the-art infrastructure

　　A stimulating, research work environment where quality, professionalism and team spirit are

　　encouraged

　　The opportunity to interact with several world-class investigators at our VIB-KU Leuven Center for Cancer Biology (CCB), in Belgium (through our established network and research consortia) and abroad.

　　How to apply?

　　Please complete the online application procedure on VIB jobsite - see http://www.vib.be/en/jobs/Page... - and include:

　　A detailed CV, including a list of your scientific publications

　　An elaborate cover letter describing your motivation

　　Contact information of 2 referees

　　Applications sent by email will not be considered.

　　For more information, please contact Patrizia Agostinis.

　　Application deadline: July 30th, 2019.

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