Postdoctoral Research Associate

Washington University in St. Louis (WUSTL)

Saint Louis, MO, United States

Posted about 3 hours agoExpires on November 24, 2020

A postdoctoral position is available in the laboratory of Dr. Irfan Lodhi in the Division of Endocrinology, Metabolism & Lipid Research at Washington University School of Medicine. The Lodhi lab uses cutting-edge technologies, including CRISPR/Cas9, next-generation sequencing, lipidomics and proteomics. The overall goal of the lab is to understand lipid metabolism pathways and their relationship to metabolic diseases, including diabetes and obesity. For more information, please visit our lab website (LodhiLab.org).

The candidate must have a PhD in physiology, molecular biology, cell biology, biochemistry or a related field with strong experience in molecular biology demonstrated by publication in reputable journals. Experience in mouse handling and surgery is desirable, but not required. Willingness to learn these techniques is preferred. Skills in independent analytical thinking, experimental design, troubleshooting, and the ability to effectively communicate with the laboratory staff and investigators are highly desired. Qualified candidates are invited to contact Dr. Lodhi (ilodhi@wustl.edu) with CV and names of three references.

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Selected References

1.    He A, Chen X, Tan M, Chen Y, Zhang X, Dean JD, Razani B, Lodhi IJ. Acetyl-CoA Derived from Hepatic Peroxisomal b-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation. Molecular Cell 2020, 79(1):30-42.

2.    Park H, He A, Tan M, Dean JM, Johnson JM, Chen Y, Zhang X, Hsu FF, Razani B, Funai F, Lodhi IJ. Peroxisome-Derived Lipids Regulate Adipose Thermogenesis by Mediating Cold-Induced Mitochondrial Fission. Journal of Clinical Investigation 2019 129(2):694-711.

3.    Lodhi IJ#, Dean JM, He A, Park H, Tan M, Feng C, Song H, Hsu FF, Semenkovich CF. PexRAP inhibits PRDM16-mediated thermogenic gene expression. Cell Reports 2017 Sep 19;20(12):2766-2774. #Corresponding author.

4.    Park H, He A, Lodhi IJ. Lipid regulators of thermogenic fat activation. Trends in Endocrinology & Metabolism 2019 Oct; 30(10):710-723.

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